Department of Pediatrics, Gulhane Military Medical Academy, Ankara, Turkey.
Biol Trace Elem Res. 2011 Oct;143(1):188-95. doi: 10.1007/s12011-010-8878-8. Epub 2010 Oct 19.
The quality of the diet of obese children is poor. Eating habits may alter micronutrient status in obese patients. In this study, we determined the serum levels of selenium, zinc, vanadium, molybdenum, iron, copper, beryllium, boron, chromium, manganese, cobalt, silver, barium, aluminum, nickel, cadmium, mercury, and lead in obese Turkish children. Thirty-four obese and 33 healthy control subjects were enrolled in the study. Serum vanadium and cobalt levels of obese children were significantly lower than those of the control group (0.244 ± 0.0179 vs. 0.261 ± 0.012 μg/l, p < 0.001, and 0.14 ± 0.13 vs. 0.24 ± 0.15 μg/l, p = 0.011, respectively). There was no significant difference between groups regarding the other serum trace element levels. In conclusion, there may be alterations in the serum levels of trace elements in obese children and these alterations may have a role in the pathogenesis of obesity.
肥胖儿童的饮食质量较差。饮食习惯可能会改变肥胖患者的微量营养素状态。在这项研究中,我们测定了肥胖的土耳其儿童的血清硒、锌、钒、钼、铁、铜、铍、硼、铬、锰、钴、银、钡、铝、镍、镉、汞和铅水平。研究纳入了 34 名肥胖儿童和 33 名健康对照组。肥胖儿童的血清钒和钴水平明显低于对照组(0.244±0.0179 对 0.261±0.012μg/l,p<0.001,和 0.14±0.13 对 0.24±0.15μg/l,p=0.011)。两组间其他血清微量元素水平无显著差异。结论:肥胖儿童的血清微量元素水平可能发生改变,这些改变可能在肥胖的发病机制中起作用。