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Pharmaceutical application of biomedical polymers. XXIX. Preliminary study on film dosage form prepared from chitosan for oral drug delivery.

作者信息

Miyazaki S, Yamaguchi H, Takada M, Hou W M, Takeichi Y, Yasubuchi H

机构信息

Faculty of Pharmaceutical Sciences, Higashi-Nippon-Gakuen University, Hokkaido, Japan.

出版信息

Acta Pharm Nord. 1990;2(6):401-6.

PMID:2095798
Abstract

The potential of chitosan films containing diazepam as an oral drug delivery was investigated in rabbits. The results indicated that a film composed of a 1:0.5 drug-chitosan mixture might be an effective dosage form that is equivalent to the commercial tablet dosage forms. The ability of chitosan to form films may permit its use in the formulation of film dosage forms, as an alternative to pharmaceutical tablets.

摘要

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