Felt O, Buri P, Gurny R
School of Pharmacy, University of Geneva, Switzerland.
Drug Dev Ind Pharm. 1998 Nov;24(11):979-93. doi: 10.3109/03639049809089942.
The aim of this review is to give an insight into the many potential applications of chitosan as a pharmaceutical drug carrier. The first part of this review concerns the principal uses of chitosan as an excipient in oral formulations (particularly as a direct tableting agent) and as a vehicle for parenteral drug delivery devices. The use of chitosan to manufacture sustained-release systems deliverable by other routes (nasal, ophthalmic, transdermal, and implantable devices) is discussed in the second part.
本综述的目的是深入了解壳聚糖作为药物载体的众多潜在应用。本综述的第一部分涉及壳聚糖在口服制剂中作为辅料（特别是作为直接压片剂）以及作为肠胃外给药装置载体的主要用途。第二部分讨论了壳聚糖用于制造可通过其他途径（鼻腔、眼部、透皮和植入式装置）给药的缓释系统。
