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[单克隆抗A和抗B抗体标准的要求]

[Requirements for standards for monoclonal anti-A and anti-B antibodies].

作者信息

Májský A

机构信息

Technická spolupráce M. Machácková, Ustav hematologie a krevní transfúze, Praha.

出版信息

Cesk Farm. 1990 Nov;39(9):409-11.

PMID:2095983
Abstract

On the model of the Soviet monoclonal anti-A and anti-B antibody--erythrocytes of the groups A1, A2, A1B and A2B the conditions for the elaboration of the branch standard for anti-A and anti-B monoclonal antibodies were worked out. In comparison with the standard for human sera determining the ABO groups, the requirement for avidity can be increased, furthermore it seems necessary to determine the percentage of non-A blood cells in the A2B group, which should not exceed 30%, and the percentage of non-B blood cells in A1B erythrocytes, which should not exceed 10%.

摘要

以苏联单克隆抗 A 和抗 B 抗体——A1、A2、A1B 和 A2B 血型红细胞为模型,制定了抗 A 和抗 B 单克隆抗体分支标准的制定条件。与用于确定 ABO 血型的人血清标准相比,可以提高对亲和力的要求,此外,似乎有必要确定 A2B 血型中非 A 血细胞的百分比,该百分比不应超过 30%,以及 A1B 红细胞中非 B 血细胞的百分比,该百分比不应超过 10%。

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