Peracchia A, Bardini R, Ruol A, Castoro C, Tiso E, Asolati M
Istituto di Clinica Chirurgica, Università degli studi di Padova.
Chirurgie. 1990;116(4-5):351-7; discussion 357-8.
From 1975 to 1988, we observed 169 patients with a carcinoma of the cervical esophagus, 85 with a carcinoma involving the hypopharynx and the cervical esophagus, and 27 with a carcinoma of the cervical esophagus occurring after laryngectomy for laryngeal carcinoma. The average age was 57.5 years (41-73). Exploration was surgical for 167 patients (operability ratio 59.5%), and the lesion was resected in 152 cases (resectability ratio 81.1%). Resection was complete in 129 patients (84.5%) and palliative in 23 (14.5%). A laryngopharyngoesophagectomy involving the cervical esophagus and requiring the transplantation of a free intestinal loop was performed in 33 cases, with an operative mortality rate of 6.1%. Pharyngolaryngectomy with total esophagectomy was performed in 101 patients, and the digestive tract was reconstructed by means of pharyngogastrostomy or pharyngocolostomy (respectively 85 and 16 cases) with an operative mortality rate of 12.9% and 18.3%, respectively. Complete esophagectomy without laryngectomy was performed for 18 patients with carcinoma of the distal cervical esophagus who refused laryngectomy, the hospital mortality rate being of 5.5%. The actuarial survival rate after 5 years (not including operative mortality) was 15.8%. Better results were achieved after complete resection for carcinoma of the hypopharynx than for carcinoma of the cerebral esophagus. The actuarial survival rates after 2 and 5 years were 59% vs. 26% and 43% vs. 17% respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
1975年至1988年期间,我们观察了169例颈段食管癌患者、85例累及下咽和颈段食管的癌患者以及27例喉癌喉切除术后发生颈段食管癌的患者。平均年龄为57.5岁(41 - 73岁)。167例患者接受了手术探查(可手术率为59.5%),其中152例病变被切除(切除率为81.1%)。129例患者切除完整(84.5%),23例为姑息性切除(14.5%)。33例行涉及颈段食管的喉咽食管切除术并需游离肠袢移植,手术死亡率为6.1%。101例患者行喉咽切除术加全食管切除术,分别采用咽胃吻合术或咽结肠吻合术重建消化道(分别为85例和16例),手术死亡率分别为12.9%和18.3%。18例颈段食管远端癌患者拒绝行喉切除术,行单纯食管切除术,医院死亡率为5.5%。5年精算生存率(不包括手术死亡率)为15.8%。下咽癌完整切除后的效果优于颈段食管癌。2年和5年精算生存率分别为59%对26%以及43%对17%。(摘要截断于250字)