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心肌梗死患者6-酮-前列腺素F1α和血栓素B2的变化

Changes in 6 keto PGF1 alpha and TXB2 in patients with myocardial infarction.

作者信息

Madan Z M, Sainani G S

机构信息

Grant Medical College.

出版信息

J Assoc Physicians India. 1994 Feb;42(2):111-2.

PMID:7860468
Abstract

A study was carried out on the plasma levels of 6 Keto PGF1 alpha and Thromboxane B2 (TXB2) in patients with acute myocardial infarction. Our results showed a generalized increase in the levels after acute myocardial infarction. The 6 Keto PGF1 alpha levels increased twice as compared to control values while the TXB2 levels increased nine times as compared to control values. The prostaglandin levels were found to increase from day 1 to day 3 and further from day 3 to day 7. In most of the patients with uncomplicated myocardial infarction the 6 Keto PGF1 alpha levels were higher than the TXB2 levels. In patients with myocardial infarction accompanied by arrhythmias the TXB2 levels dominated over the 6 Keto PGF1 alpha levels.

摘要

对急性心肌梗死患者的血浆6-酮-前列腺素F1α和血栓素B2(TXB2)水平进行了一项研究。我们的结果显示,急性心肌梗死后这些水平普遍升高。6-酮-前列腺素F1α水平相较于对照值增加了两倍,而TXB2水平相较于对照值增加了九倍。发现前列腺素水平从第1天到第3天升高,并且从第3天到第7天进一步升高。在大多数无并发症心肌梗死的患者中,6-酮-前列腺素F1α水平高于TXB2水平。在伴有心律失常的心肌梗死患者中,TXB2水平高于6-酮-前列腺素F1α水平。

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