Despotovic S Frtunic, Siewe S, Keta A
Service de médecine de premier recours, Département de médecine communautaire et de premier recous, Genève.
Rev Med Suisse. 2010 Sep 29;6(264):1816-8, 1820.
Atrial fibrillation is the most frequent cardiac arrhythmia and its prevalence increases with age. It is essential to prevent the thromboembolic events, stroke in particular, considered as its most serious complication. Vitamin K antagonists are currently the most effective drugs to prevent them. However, despite their proven efficacy, they carry a risk of bleeding complications. Consequently, it is essential to balance individual thromboembolic risk with the hemorrhagic risk, taking into consideration age, cardiac diseases, hypertension, diabetes, history of cerebral vascular accident, history of hemorrhagic disease and also patient's compliance. The CHADS2 score is a stratification model for stroke risk in patients with non-valvular atrial fibrillation that is the easiest score to use in clinical practice and the most used one.
心房颤动是最常见的心律失常，其患病率随年龄增长而增加。预防血栓栓塞事件，尤其是中风，被认为是其最严重的并发症，这至关重要。维生素K拮抗剂是目前预防这些事件最有效的药物。然而，尽管其疗效已得到证实，但它们存在出血并发症的风险。因此，必须在考虑年龄、心脏病、高血压、糖尿病、脑血管意外史、出血性疾病史以及患者依从性的情况下，平衡个体的血栓栓塞风险和出血风险。CHADS2评分是一种用于非瓣膜性心房颤动患者中风风险分层的模型，它是临床实践中最容易使用且使用最广泛的评分。
