Department of Urology, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium.
J Pediatr Urol. 2011 Apr;7(2):170-3. doi: 10.1016/j.jpurol.2010.04.013. Epub 2010 Jun 8.
To determine the outcome of urethroplasty for failed hypospadias repair and to compare this with a matched cohort of patients treated with urethroplasty for other reasons.
Between January 2000 and August 2007, 25 patients with a failed hypospadias repair were treated with urethroplasty (A). This cohort of patients was matched with a cohort of 25 patients who underwent urethroplasty for other reasons (B). The patients were matched for stricture location, stricture length, duration of follow up and type of urethroplasty. The outcomes were analysed and compared. A P-value < 0.05 was considered statistically significant.
There were no significant differences between the two cohorts in stricture location, stricture length, follow up and previous interventions. Patients in cohort A however were significantly younger. The surgical technique used was exactly the same in A and B. Failure was observed in 7 patients (28%) in A compared to 4 patients (16%) in B (P = 0.45).
Although a higher failure rate was observed after failed hypospadias repair, this is not proof of a worse outcome for urethroplasty after failed hypospadias repair due to the lack of statistical significance.
确定失败的尿道下裂修复后尿道成形术的结果，并将其与因其他原因接受尿道成形术治疗的患者相匹配的队列进行比较。
在 2000 年 1 月至 2007 年 8 月期间，25 例失败的尿道下裂修复患者接受了尿道成形术（A 组）。该队列的患者与因其他原因接受尿道成形术治疗的 25 例患者（B 组）相匹配。患者在狭窄位置、狭窄长度、随访时间和尿道成形术类型方面进行了匹配。对结果进行了分析和比较。P 值<0.05 被认为具有统计学意义。
两组患者在狭窄位置、狭窄长度、随访时间和先前干预方面无显著差异。然而，A 组患者明显更年轻。A 组和 B 组使用的手术技术完全相同。A 组有 7 例（28%）患者发生失败，B 组有 4 例（16%）患者发生失败（P=0.45）。
尽管失败的尿道下裂修复后观察到失败率较高，但由于缺乏统计学意义，这不能证明失败的尿道下裂修复后尿道成形术的结果更差。
