化疗后索马里儿童再次感染毛首鞭形线虫：免疫刺激的相关性

Reinfection of Somali children with Trichuris trichiura after chemotherapy: relevance of immunostimulation.

作者信息

Shiddo S, Ilardi I, Mussa C, Mohamud M A, Aceti A, Leone F, Sebastiani A, Amiconi G

机构信息

Faculty of Medicine, National University of Somalia, Mogadishu.

出版信息

Trans R Soc Trop Med Hyg. 1990 Nov-Dec;84(6):832-6. doi: 10.1016/0035-9203(90)90100-s.

DOI:10.1016/0035-9203(90)90100-s

PMID:2096517

Abstract

The intestinal helminth status of an age-stratified sample (6 to 20 years old) from a Somalian community has been assessed and the typical pattern of highly aggregated parasite distribution found. A reinfection study on a sample of 40 children (treated and untreated with a pentapeptide identical to the active site of the thymic hormone thymopoietin) seemed to indicate that immunological factors play a significant role in modulating the population dynamics of infection in endemic communities.

摘要

对索马里一个社区年龄分层样本（6至20岁）的肠道蠕虫感染状况进行了评估，并发现了寄生虫分布高度聚集的典型模式。一项针对40名儿童的再感染研究（用一种与胸腺激素胸腺生成素活性位点相同的五肽进行治疗和未治疗）似乎表明，免疫因素在调节流行社区感染的种群动态中起着重要作用。