Department of Materials Science and Engineering, Zhejiang University, 38# Zheda Road, Hangzhou 310027, China.
Colloids Surf B Biointerfaces. 2011 Feb 1;82(2):637-40. doi: 10.1016/j.colsurfb.2010.09.025. Epub 2010 Oct 20.
A novel process has been developed for the preparation of a hydroxyapatite (HA) coating with a hierarchical structure on a Ti substrate. The Ti substrate was first subjected to electrolytic deposition at -1.6V (versus Ag/AgCl/KCl) in a solution of 0.042M Ca(NO(3))(2)·4H(2)O and 0.025M NH(4)H(2)PO(4) at 85°C for 3min, and then post-treated in a 0.25M NaOH solution, with the addition of 0.05M Na(3)Cit at 85°C for 5h. The experimental results showed that the coating experienced a phase conversion from octacalcium phosphate to HA after the post-treatment step. The HA coating had well-distributed, micro-sized pores comprising three-dimensional interconnected mesoporous HA belts, which would greatly increase the porosity and surface area of the coating.
一种新颖的工艺已被开发用于在 Ti 基底上制备具有分级结构的羟基磷灰石（HA）涂层。Ti 基底首先在 85°C 下于 0.042M Ca(NO(3))(2)·4H(2)O 和 0.025M NH(4)H(2)PO(4)溶液中以-1.6V（相对于 Ag/AgCl/KCl）进行 3 分钟的电解沉积，然后在后处理步骤中在 0.25M NaOH 溶液中添加 0.05M Na(3)Cit，在 85°C 下处理 5 小时。实验结果表明，后处理步骤后，涂层经历了从八钙磷酸盐到 HA 的相转化。HA 涂层具有分布均匀的微尺度孔，包含三维相互连接的介孔 HA 带，这将极大地增加涂层的孔隙率和表面积。
