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钛基植入体的离子掺杂硅酸盐生物陶瓷涂层

Ion-Doped Silicate Bioceramic Coating of Ti-Based Implant.

作者信息

Mohammadi Hossein, Sepantafar Mohammadmajid

机构信息

School of Materials and Mineral Resources Engineering, Universiti Sains Malaysia, Engineering Campus, 14300 Nibong Tebal, Penang, Malaysia.

Department of Stem Cell and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.

出版信息

Iran Biomed J. 2016 Sep;20(4):189-200. doi: 10.7508/ibj.2016.04.002. Epub 2016 Mar 16.

Abstract

Titanium and its alloy are known as important load-bearing biomaterials. The major drawbacks of these metals are fibrous formation and low corrosion rate after implantation. The surface modification of biomedical implants through various methods such as plasma spray improves their osseointegration and clinical lifetime. Different materials have been already used as coatings on biomedical implant, including calcium phosphates and bioglass. However, these materials have been reported to have limited clinical success. The excellent bioactivity of calcium silicate (Ca-Si) has been also regarded as coating material. However, their high degradation rate and low mechanical strength limit their further coating application. Trace element modification of (Ca-Si) bioceramics is a promising method, which improves their mechanical strength and chemical stability. In this review, the potential of trace element-modified silicate coatings on better bone formation of titanium implant is investigated.

摘要

钛及其合金是重要的承重生物材料。这些金属的主要缺点是植入后会形成纤维且腐蚀速率低。通过等离子喷涂等各种方法对生物医学植入物进行表面改性可改善其骨整合和临床使用寿命。不同的材料已被用作生物医学植入物的涂层,包括磷酸钙和生物玻璃。然而,据报道这些材料在临床上的成功率有限。硅酸钙(Ca-Si)的优异生物活性也被视为涂层材料。然而,它们的高降解率和低机械强度限制了其进一步的涂层应用。(Ca-Si)生物陶瓷的微量元素改性是一种很有前景的方法,可提高其机械强度和化学稳定性。在这篇综述中,研究了微量元素改性硅酸盐涂层对钛植入物更好地形成骨组织的潜力。

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