术中谱域光学相干断层扫描在玻璃体视网膜手术中的应用。
Intraoperative spectral domain optical coherence tomography for vitreoretinal surgery.
机构信息
Department of Biomedical Engineering, Duke University, 136 Hudson Hall, Durham, North Carolina 27708, USA.
出版信息
Opt Lett. 2010 Oct 15;35(20):3315-7. doi: 10.1364/OL.35.003315.
Abstract
We demonstrate in vivo human retinal imaging using an intraoperative microscope-mounted optical coherence tomography system (MMOCT). Our optomechanical design adapts an Oculus Binocular Indirect Ophthalmo Microscope (BIOM3), suspended from a Leica ophthalmic surgical microscope, with spectral domain optical coherence tomography (SD-OCT) scanning and relay optics. The MMOCT enables wide-field noncontact real-time cross-sectional imaging of retinal structure, allowing for SD-OCT augmented intrasurgical microscopy for intraocular visualization. We experimentally quantify the axial and lateral resolution of the MMOCT and demonstrate fundus imaging at a 20Hz frame rate.
摘要
我们使用术中显微镜安装的光学相干断层扫描系统（MMOCT）进行体内人视网膜成像。我们的光机设计适应了一种从徕卡眼科手术显微镜上悬挂的 Oculus 双目间接检眼镜（BIOM3），具有光谱域光学相干断层扫描（SD-OCT）扫描和中继光学元件。MMOCT 能够对视网膜结构进行宽视场非接触实时横截面成像，从而实现 SD-OCT 增强的术中显微镜，用于眼内可视化。我们实验量化了 MMOCT 的轴向和横向分辨率，并演示了以 20Hz 帧率进行的眼底成像。
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