Hunter M J, Griswold J D, Rosenberg M
Boston University Medical Center, MA.
Anesth Prog. 1990 Sep-Oct;37(5):248-51.
Rectally administered methohexital is a safe, effective sedative to ameliorate the stress of the surgical experience for the uncooperative child. The rapid onset, relatively short duration, and patient acceptance of this technique make it applicable for many pediatric outpatient procedures. Induction doses of 20-30 mg/kg of a 10% methohexital solution can produce sleep in 7-8 minutes. In some situations, the rectal route of administration has advantages over more commonly used techniques.
直肠给药的美索比妥是一种安全、有效的镇静剂,可减轻不合作儿童手术过程中的应激反应。该技术起效迅速、持续时间相对较短且患者易于接受,适用于许多儿科门诊手术。10%美索比妥溶液的诱导剂量为20 - 30mg/kg,可在7 - 8分钟内诱导睡眠。在某些情况下,直肠给药途径比更常用的技术具有优势。