Institute of Cardiology, 2nd Ischaemic Heart Disease Department, Warsaw, Poland.
Kardiol Pol. 2010 Oct;68(10):1133-9.
atrial fibrillation (AF) is difficult to cure and significantly affects quality of life was well as emotional status of patients.
to evaluate quality of life and depression level in patients with various patterns of AF.
we studied 150 consecutive patients with AF aged 35-83 years, including 61 patients with paroxysmal AF, 46 patients with persistent AF, and 43 patients with permanent AF. The control group included 70 healthy persons (mean age: 55.5 ± 14.5 years). Quality of life was estimated using the Nottingham Health Profile questionnaire. Risk of depression occurrence was estimated using the Beck Depression Inventory scale. Physical abilities, energy level, pain, emotional reactions, sleep, social isolation, problems with work, family life and sexual life were analysed.
the mean age of patients with paroxysmal AF was higher in comparison to patients with permanent AF (68.4 ± 9.4 vs 62.0 ± 9.2 years, p < 0.05). In patients with all AF forms, the prevalence of symptoms indicating depression was significantly higher in comparison with control group (paroxysmal AF: 10.8 ± 5.8%, persistent AF: 10.0 ± 6.4%, permanent AF: 10.1 ± 7.2% vs 5.7 ± 5.8% in controls, p < 0.01). The level of depression was higher in women regardless of AF form (p < 0.005). Patients with paroxysmal and permanent AF had lower scores of emotional reactions (p < 0.05) and social isolation (p < 0.05) in comparison with the control group. All patients with AF had lower scores of energy level in comparison with the control group (paroxysmal AF: 1.2 ± 0.2, persistent AF: 1.1 ± 0.2, permanent AF: 1.2 ± 0.2 vs 0.5 ± 0.1 in controls, p < 0.005). Patients with paroxysmal, persistent and permanent AF had greater degree of activity limitations than the control group (1.8 ± 0.2, 1.7 ± 0.3, 2.1 ± 0.3, respectively, vs 1.0 ± 0.2, p < 0.005). Limitations of work were detected in 28.6-35.9% of patients with various forms of AF, sex life disturbances in 23.8-33.9% of patients, and family life problems in 10.3-21.4% of patients. The lowest results of these scores were noted in patients with paroxysmal AF.
atrial fibrillation, independently of its form, has substantial impact on the risk of depression occurrence. Patients with paroxysmal and permanent AF had lower self-evaluation of their energy level. In all studied groups of AF patients, the arrhythmia significantly limited quality of life, especially sexual life as well as professional and home activity.
心房颤动（AF）难以治愈，严重影响患者的生活质量和情绪状态。
评估不同类型 AF 患者的生活质量和抑郁水平。
我们研究了 150 例年龄在 35-83 岁的连续 AF 患者，包括 61 例阵发性 AF 患者、46 例持续性 AF 患者和 43 例永久性 AF 患者。对照组包括 70 名健康人（平均年龄：55.5±14.5 岁）。使用诺丁汉健康调查问卷评估生活质量。使用贝克抑郁量表评估抑郁发生风险。分析身体能力、能量水平、疼痛、情绪反应、睡眠、社会隔离、工作问题、家庭生活和性生活。
与永久性 AF 患者相比，阵发性 AF 患者的平均年龄更高（68.4±9.4 岁比 62.0±9.2 岁，p<0.05）。在所有 AF 形式的患者中，与对照组相比，表明抑郁的症状更常见（阵发性 AF：10.8±5.8%，持续性 AF：10.0±6.4%，永久性 AF：10.1±7.2%比 5.7±5.8%，p<0.01）。无论 AF 形式如何，女性的抑郁水平均较高（p<0.005）。与对照组相比，阵发性和永久性 AF 患者的情绪反应（p<0.05）和社会隔离（p<0.05）评分较低。所有 AF 患者的能量水平评分均低于对照组（阵发性 AF：1.2±0.2，持续性 AF：1.1±0.2，永久性 AF：1.2±0.2 比 0.5±0.1，p<0.005）。与对照组相比，阵发性、持续性和永久性 AF 患者的活动受限程度更严重（分别为 1.8±0.2、1.7±0.3、2.1±0.3，p<0.005）。在 28.6-35.9%的各种形式的 AF 患者中发现了工作受限，在 23.8-33.9%的患者中发现了性生活障碍，在 10.3-21.4%的患者中发现了家庭生活问题。在阵发性 AF 患者中，这些评分的最低结果。
AF 无论其形式如何，都会显著增加抑郁发生的风险。阵发性和永久性 AF 患者的自我能量评估较低。在所有研究的 AF 患者组中，心律失常严重限制了生活质量，尤其是性生活以及职业和家庭活动。
