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成人疑似首次发作后,何时应进行睡眠剥夺脑电图检查?

When should a sleep-deprived EEG be performed following a presumed first seizure in adults?

机构信息

Epilepsy Clinic, Department of Neurology, Assaf Harofeh Medical Center, Zerifin, Israel.

出版信息

Acta Neurol Scand. 2011 Sep;124(3):202-5. doi: 10.1111/j.1600-0404.2010.01453.x. Epub 2010 Oct 25.

DOI:10.1111/j.1600-0404.2010.01453.x
PMID:20969558
Abstract

OBJECTIVES

To evaluate the effect of the interval between the seizure and the EEG recording on the yield of early sleep-deprived EEG (SD-EEG) in patients admitted following a presumed first seizure.

MATERIALS AND METHODS

We retrospectively reviewed the EEG recordings and medical records of patients admitted to the Neurology Department in Assaf Harofeh Medical Center because of a presumed first seizure during a 3-year period between 2006 and 2009 and who had a SD-EEG following a first routine EEG without epileptiform discharges (EDs).

RESULTS

The study group included 78 patients aged 18-78 years (mean 35 ± 17). Previous seizures were recognized through repeated history in 32 (41%) patients. EDs were recorded in the SD-EEG in 16 (21%) patients: 13/46 (28%) with a SD-EEG performed within 3 days following the seizure and 3/32 (9%) with a later SD-EEG (P = 0.042) and in 10/32 (31%) patients in whom previous seizures were recognized and 6/46 (13%) with a first seizure (P = 0.05).

CONCLUSIONS

EDs in the SD-EEG following a first diagnosed seizure occur more commonly when the test is performed within 3 days following a first seizure or when previous seizures are recognized.

摘要

目的

评估癫痫发作与 EEG 记录之间的时间间隔对疑似首次癫痫发作后入院患者早期睡眠剥夺 EEG(SD-EEG)产量的影响。

材料和方法

我们回顾性地审查了 2006 年至 2009 年期间在 Assaf Harofeh 医疗中心神经病学部门因疑似首次癫痫发作而入院且在首次常规 EEG 无癫痫样放电(EDs)后进行 SD-EEG 的患者的 EEG 记录和病历。

结果

研究组包括 78 名年龄在 18-78 岁之间的患者(平均年龄 35 ± 17)。32 名(41%)患者通过重复病史确认了之前的癫痫发作。16 名(21%)患者在 SD-EEG 中记录到 EDs:46 名中 13 名(28%)在癫痫发作后 3 天内进行 SD-EEG,32 名中 3 名(9%)进行较晚的 SD-EEG(P = 0.042),其中 10 名(31%)患者在之前的癫痫发作中得到了确认,而 46 名中 6 名(13%)患者出现了首次癫痫发作(P = 0.05)。

结论

在首次诊断性癫痫发作后进行的 SD-EEG 中,如果在首次癫痫发作后 3 天内进行测试或确认之前有癫痫发作,EDs 更常见。

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