Total Skin & Beauty Dermatology Center, PC, Birmingham, Alabama, USA.
Dermatol Surg. 2010 Nov;36 Suppl 3:1809-16. doi: 10.1111/j.1524-4725.2010.01739.x.
Various scoring techniques prone to subjective interpretation have been used to evaluate soft tissue augmentation of nasolabial folds (NLFs).
To design and validate a reliable wrinkle assessment scoring scale.
Six photographed wrinkles of varying severity were electronically copied onto the same facial image to become a 6-point grading scale (GGS). A pilot training program (13 investigators) determined reliability, and a 12-week multicenter survey study validated the GGS scoring method.
Pilot study inter- and intrarater scoring reliability were high (weighted kappa scores of 0.85 and 0.86, respectively). Seventy-five percent of survey investigators and independent review panel (IRP) members considered a GGS score difference of 0.5 to be a minimally perceivable difference. Interrater weighted kappa scores were 0.91 for the IRP and 0.80 for investigators. Intrarater agreements after repeat testing were 0.91 and 0.89, respectively. The baseline "live" assessment GGS mean score was 3.34, and the baseline blinded photographic assessment GGS mean score was 2.00 for the IRP and 2.16 for the investigators.
The GGS is a reproducible method of grading the severity of NLF wrinkles. Treatment effectiveness of a dermal filler can be reliably evaluated using the GGS by comparing "live" assessments with the standard GGS photographic panel.
各种评分技术容易受到主观解释的影响，已被用于评估鼻唇沟（NLF）的软组织填充效果。
设计并验证一种可靠的皱纹评估评分量表。
将六个不同严重程度的皱纹电子复制到同一张面部图像上，形成 6 分等级量表（GGS）。一个试点培训计划（13 名调查员）确定了可靠性，为期 12 周的多中心调查研究验证了 GGS 评分方法。
试点研究的组内和组间评分可靠性较高（加权kappa 评分分别为 0.85 和 0.86）。75%的调查员和独立审查小组（IRP）成员认为 GGS 评分差异为 0.5 是可以感知到的最小差异。IRP 的组间加权kappa 评分和调查员的组间加权kappa 评分分别为 0.91 和 0.80。重复测试后的组内一致性分别为 0.91 和 0.89。基线“活体”评估 GGS 平均得分为 3.34，IRP 的基线盲法摄影评估 GGS 平均得分为 2.00，调查员的基线盲法摄影评估 GGS 平均得分为 2.16。
GGS 是一种可重复的 NLF 皱纹严重程度分级方法。通过比较“活体”评估与标准 GGS 摄影面板，可以使用 GGS 可靠地评估真皮填充剂的治疗效果。
