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移动体外膜肺氧合单元扩大了心脏辅助手术项目。

Mobile extracorporeal membrane oxygenation unit expands cardiac assist surgical programs.

机构信息

Cardiac Surgery Department, Timone's Adults Hospital, Marseille, France.

出版信息

Ann Thorac Surg. 2010 Nov;90(5):1548-52. doi: 10.1016/j.athoracsur.2010.06.091.

Abstract

BACKGROUND

Extracorporeal membrane oxygenation (ECMO) is an effective technique to provide emergency mechanical circulatory or respiratory assistance in critically ill patients. A Mobile Remote Cardiac Assist unit was created to implant ECMO in patients from outside our institution and bring them back in our intensive care unit for follow-up when stabilized. This study was undertaken to evaluate the feasibility and the preliminary results of this procedure.

METHODS

Between March 2006 and June 2008, 38 consecutive patients with acute cardiac or respiratory failure were implanted with percutaneous ECMO. The logistic concerns, indications, complications, and outcomes of these patients were analyzed.

RESULTS

There were no logistic or technical problems during the round trip or ECMO implantation. Mean distance from our intensive care unit was 68 km (1 to 230). Maximal time limit between the phone call and implantation was 90 minutes. The indications were fulminant myocarditis, pharmacologic suicide attempt, acute myocardial infarction, postpartum cardiopathy, end-stage cardiomyopathy, with left ventricular ejection fraction of 0.19 ± 0.05 (n = 32), or acute respiratory distress syndrome without cardiac failure (n = 6). Patients received a percutaneous venoarterial femoral ECMO with immediate reperfusion of the limb or venovenous ECMO for isolated lung failure. Seventeen patients (45%) were successfully weaned from ECMO after 9.4 ± 8.7 days. Four patients (11%) were transplanted. One patient was switched to a left ventricular assist device and was then successfully transplanted. Twenty-one patients (55%) survived to hospital discharge.

CONCLUSIONS

The Mobile Cardiac Assist unit allowed emergency implantation of ECMO support in remote institutions without any logistic or technical problems.

摘要

背景

体外膜肺氧合(ECMO)是为危重病患者提供紧急机械循环或呼吸辅助的有效技术。创建了一个移动远程心脏辅助单元,以便在我们的机构外为患者植入 ECMO,并在稳定后将他们带回我们的重症监护病房进行后续治疗。本研究旨在评估该程序的可行性和初步结果。

方法

2006 年 3 月至 2008 年 6 月,连续 38 例急性心或呼吸衰竭患者接受了经皮 ECMO 植入。分析了这些患者的逻辑问题、适应证、并发症和结局。

结果

在往返或 ECMO 植入过程中没有逻辑或技术问题。我们重症监护室的平均距离为 68 公里(1 至 230 公里)。从电话到植入的最长时间限制为 90 分钟。适应证为暴发性心肌炎、药物自杀企图、急性心肌梗死、产后心脏病、终末期心肌病,左心室射血分数为 0.19±0.05(n=32),或无心力衰竭的急性呼吸窘迫综合征(n=6)。患者接受了经皮股动静脉 ECMO,立即再灌注肢体或单纯肺衰竭的静脉-静脉 ECMO。17 例(45%)患者在 9.4±8.7 天后成功脱离 ECMO。4 例(11%)患者接受了移植。1 例患者被切换到左心室辅助装置,随后成功移植。21 例(55%)患者存活至出院。

结论

移动心脏辅助单元允许在没有任何逻辑或技术问题的情况下在远程机构紧急植入 ECMO 支持。

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