Center for Cardiac Intensive Care, Beijing Anzhen Hospital, Capital Medical University, Anzhen Road, Beijing 100029, China.
Biomed Res Int. 2016;2016:7263187. doi: 10.1155/2016/7263187. Epub 2016 May 16.
Heart failure (HF) can be defined as cardiac structural or functional abnormality leading to a series of symptoms due to deficiency of oxygen delivery. In the clinical practice, acute heart failure (AHF) is usually performed as cardiogenic shock (CS), pulmonary edema, and single or double ventricle congestive heart failure. CS refers to depressed or insufficient cardiac output (CO) attributable to myocardial infarction, fulminant myocarditis, acute circulatory failure attributable to intractable arrhythmias or the exacerbation of chronic heart failure, postcardiotomy low CO syndrome, and so forth. Epidemiological studies have shown that CS has higher in-hospital mortality in patients with AHF. Besides, we call the induced, sustained circulatory failure even after administration of high doses of inotropes and vasopressors refractory cardiogenic shock. In handling these cases, mechanical circulatory support devices are usually needed. In this review, we discuss the current application status and clinical points in utilizing extracorporeal membrane oxygenation (ECMO).
心力衰竭(HF)可定义为心脏结构或功能异常,导致一系列由于供氧不足而出现的症状。在临床实践中,急性心力衰竭(AHF)通常表现为心源性休克(CS)、肺水肿和单心室或双心室充血性心力衰竭。CS 是指由于心肌梗死、暴发性心肌炎、难以控制的心律失常或慢性心力衰竭恶化导致的心肌输出量(CO)降低或不足、心脏手术后低 CO 综合征等引起的。流行病学研究表明,CS 是 AHF 患者住院死亡率较高的原因之一。此外,我们还将即使给予大剂量正性肌力药物和血管加压素后仍持续存在的循环衰竭称为难治性心源性休克。在处理这些病例时,通常需要使用机械循环支持设备。在本综述中,我们讨论了体外膜肺氧合(ECMO)的当前应用现状和临床要点。