Militzer K, Herberg L, Büttner D
Central Animal Laboratory, University of Essen, F.R.G.
Exp Pathol. 1990;40(3):139-53. doi: 10.1016/s0232-1513(11)80337-3.
The ontogenesis of the organ weights of the liver, kidneys, adrenals, testes and ovaries as well as the blood glucose and plasma insulin levels were studied in a total of 464 golden hamsters of both sexes of the acromelanic white inbred strain Bio 1.5 and agouti coloured outbred strain Han:AURA. Familial and seasonal influences were excluded by means of randomisation (25 groups from 1-365 days of life). Body weight development was found to be sigmoid and showed significant differences in terms of age, sex, and strain. Liver and kidney weights developed in parallel. Here, too, strain differences (agoutis greater than acromelanics) were seen, and sex differences were observed in the case of the kidneys (females greater than males). The increased adrenal weight in male hamsters compared to females was in accordance with species- but not rodent-typical behaviour. Both the testes and ovarian weights varied considerably. Age as well as, in part, strain differences were seen in the case of the blood glucose and insulin levels. The continual development of body and organ weight could be explained in terms of physiological changes.
在总共464只黑肢端白色近交系Bio 1.5和野生色远交系Han:AURA的两性金黄仓鼠中，研究了肝脏、肾脏、肾上腺、睾丸和卵巢的器官重量的个体发生，以及血糖和血浆胰岛素水平。通过随机分组（1至365日龄的25组）排除了家族和季节影响。发现体重发育呈S形，在年龄、性别和品系方面存在显著差异。肝脏和肾脏重量平行发育。同样，也观察到了品系差异（野生色大于黑肢端色），并且在肾脏方面观察到了性别差异（雌性大于雄性）。与雌性相比，雄性仓鼠肾上腺重量增加符合物种典型行为，但不符合啮齿动物典型行为。睾丸和卵巢重量均有很大差异。在血糖和胰岛素水平方面可以看到年龄差异，部分还有品系差异。身体和器官重量的持续发育可以从生理变化的角度来解释。
