Fang Jun, Ma Da, Zhong Jun, Zhu Bin, Ding Guang-hong, Fu Li-ming, Cui Cai-lian, Han Ji-sheng
Neuroscience Research Institute, Peking University, Bejing, China.
Zhonghua Yi Xue Za Zhi. 2010 Jun 1;90(21):1472-6.
To assess the efficacy of transcutaneous electrical acupoint stimulation (TEAS) in preventing the relapse of detoxified heroin users in a period of 12 months.
A total of 164 rehabilitating heroin users in Shanghai area were recruited after compulsory detoxification treatment for a period ranging from 3 months to 3 years. The TEAS was executed by the device named Han's acupoint nerve stimulator (HANS). The patients were treated with HANS for at least 3 months. All the subjects were then followed up for one year and relapse was monitored by monthly heroin/morphine urinalysis.
Of 164 rehabilitating former heroin addicts, 53 remained drug-free at the end of 12 months observation period as judged by negative urinalysis while 35 become relapsed as documented by positive urine tests. The rest 76 dropped off due to various reasons and were all counted into the category of "relapsed". Thus, our data indicated 32.3% rehabilitating heroin users could stay sober for at least one year, which is significantly higher than the existing reports that less than 5% detoxified abusers would stay drug free for one year with no further intervention. No obvious correlation was found between the susceptibility of relapse and the duration of compulsory detoxification.
Compared to the existing literatures, our results indicate that HANS could produce a marked decrease of the relapse rate of rehabilitating heroin users after compulsory detoxification.
评估经皮穴位电刺激(TEAS)在12个月内预防戒毒海洛因使用者复吸的疗效。
招募了上海地区164名接受强制戒毒治疗3个月至3年的康复期海洛因使用者。经皮穴位电刺激由名为韩氏穴位神经刺激仪(HANS)的设备执行。患者接受韩氏穴位神经刺激仪治疗至少3个月。然后对所有受试者进行一年的随访,并通过每月的海洛因/吗啡尿液分析监测复吸情况。
在164名康复期前海洛因成瘾者中,12个月观察期结束时,53人尿液分析呈阴性,判定为未复吸;35人尿液检测呈阳性,记录为复吸。其余76人因各种原因退出,均计入“复吸”类别。因此,我们的数据表明,32.3%的康复期海洛因使用者能够保持清醒至少一年,这显著高于现有报告中未经进一步干预情况下不到5%的戒毒滥用者能保持一年无毒品状态的比例。复吸易感性与强制戒毒时长之间未发现明显相关性。
与现有文献相比,我们的结果表明,韩氏穴位神经刺激仪可显著降低强制戒毒后康复期海洛因使用者的复吸率。