CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, Key Laboratory of Optoelectronic Science and Technology in Anhui Province, University of Science and Technology of China, Hefei, Anhui 230026, People's Republic of China.
ACS Nano. 2010 Nov 23;4(11):6387-94. doi: 10.1021/nn1016605. Epub 2010 Oct 25.
We report herein the development of a highly robust, quantitative, sensitive, and naked eye colorimetric detection method for different isomers of aromatic compounds using β-CD-modified silver nanoparticle (AgNPs) probes. This assay relies on the distance-dependent optical properties of Ag nanoparticles and the different inclusion binding strength of the aromatic guests to β-CD host. In the presence of different isomers of aromatic compounds, AgNPs could be rapidly induced to aggregate, thereby resulting in apricot-to-red color change. The variety and concentration of different isomers of aromatic compounds could be determined by monitoring with the naked eye or a UV-vis spectrometer. The present detection limit for different isomers of aromatic compounds is 5 × 10(-5) M. We believe that the surface architectures of AgNPs after the introduction of the CD-based host-guest recognition would be applicable for a range of chemical and bioanalytical molecular sensing systems in aqueous media.
我们在此报告了一种使用β-环糊精修饰的银纳米粒子（AgNPs）探针，用于检测不同芳香族化合物异构体的高灵敏、定量、肉眼比色检测方法的开发。该方法依赖于 Ag 纳米粒子的距离相关光学性质和芳香族客体与β-CD 主体的不同包合结合强度。在存在不同芳香族化合物异构体的情况下，AgNPs 可以迅速诱导聚集，从而导致颜色从杏色变为红色。通过肉眼或紫外-可见分光光度计监测，可以确定不同芳香族化合物异构体的种类和浓度。该检测方法对不同芳香族化合物异构体的检测限为 5×10^(-5)M。我们相信，在引入基于 CD 的主客体识别后，AgNPs 的表面结构将适用于一系列在水相中的化学和生物分析分子传感系统。
