Oliveira Elisângela Gomes de Lima, de Oliveira Helinando Pequeno
Instituto de Pesquisa em Ciência dos Materiais, Universidade Federal do Vale do São Francisco, 48902-300 Juazeiro, Bahia, Brazil.
ACS Omega. 2025 Jun 4;10(23):23943-23956. doi: 10.1021/acsomega.5c03312. eCollection 2025 Jun 17.
The inclusion complex formation of β-cyclodextrin/silver nanoparticles uses superior optical, electrical, and structural properties of AgNPs and the singular hydrophobic cage/hydrophilic external surface of the β-cyclodextrin, enabling several properties such as controlled aggregation degree, scattering of light, and adsorption of species. Consequently, several applications are favored, ranging from antimicrobial and antibiofilm agents to analyte trace detectors based on fluorescence, scattering of light, and electrochemical responses as single or combined multimode sensing elements. Herein, applications based on guest-host complexes are discussed, focusing on the potential and limitations of each technique in developing highly sensitive and low-cost templates for identification, adsorption, and quantification of different target systems. The potential of multisensing templates and electroenhanced antibacterial supports for AgNPs/β-CD incorporation is discussed as a promising strategy to reach outstanding performance for sensors and active antibacterial sensors.
β-环糊精/银纳米颗粒包合物的形成利用了银纳米颗粒卓越的光学、电学和结构特性以及β-环糊精独特的疏水笼/亲水外表面，从而具备诸如可控聚集度、光散射和物质吸附等多种特性。因此，出现了多种应用，从抗菌和抗生物膜剂到基于荧光、光散射和电化学响应的分析物痕量检测器，可作为单一或组合的多模式传感元件。本文讨论了基于客体-主体复合物的应用，重点关注每种技术在开发用于识别、吸附和定量不同目标系统的高灵敏度和低成本模板方面的潜力和局限性。还讨论了将银纳米颗粒/β-环糊精掺入多传感模板和电增强抗菌载体的潜力，这是一种有望实现传感器和活性抗菌传感器卓越性能的策略。
