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子宫颈癌患者前哨淋巴结活检:准备好用于临床了吗?文献综述

Sentinel lymph node biopsy in uterine cervical cancer patients: ready for clinical use? A review of the literature.

作者信息

Palla Viktoria-Varvara, Karaolanis Georgios, Moris Demetrios, Antsaklis Aristides

机构信息

1st Department of Obstetrics and Gynecology, School of Medicine, National & Kapodistrian University of Athens, "Alexandra" General Hospital, Athens, Greece.

2nd Department of Surgery, Vascular Surgery Unit, Laiko General Hospital, Medical School of Athens, Athens, Greece.

出版信息

ISRN Surg. 2014 Jan 16;2014:841618. doi: 10.1155/2014/841618. eCollection 2014.

DOI:10.1155/2014/841618
PMID:24527233
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3914400/
Abstract

Sentinel lymph node biopsy has been widely studied in a number of cancer types. As far as cervical cancer is concerned, this technique has already been used, revealing both positive results and several issues to be solved. The debate on the role of sentinel lymph node biopsy in cervical cancer is still open although most of the studies have already revealed its superiority over complete lymphadenectomy and the best handling possible of the emerging practical problems. Further research should be made in order to standardize this method and include it in the clinical routine.

摘要

前哨淋巴结活检已在多种癌症类型中得到广泛研究。就宫颈癌而言,这项技术已经被应用,既显示出了积极的结果,也暴露出了一些有待解决的问题。尽管大多数研究已经揭示了前哨淋巴结活检在宫颈癌中的作用优于根治性淋巴结清扫术以及对新出现的实际问题的最佳处理方式,但关于其在宫颈癌中作用的争论仍在继续。应该进行进一步的研究,以便规范该方法并将其纳入临床常规。

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本文引用的文献

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Bilateral ultrastaging of sentinel lymph node in cervical cancer: Lowering the false-negative rate and improving the detection of micrometastasis.宫颈癌前哨淋巴结双侧超分期:降低假阴性率和提高微转移检测率。
Gynecol Oncol. 2012 Dec;127(3):462-6. doi: 10.1016/j.ygyno.2012.08.035. Epub 2012 Aug 31.
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A prospective single-center study of sentinel lymph node detection in cervical carcinoma: is there a place in clinical practice?宫颈癌前哨淋巴结检测的前瞻性单中心研究:在临床实践中有一席之地吗?
Int J Gynecol Cancer. 2012 Jul;22(6):1044-9. doi: 10.1097/IGC.0b013e318253a9c9.
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Sentinel lymph node status in patients with locally advanced cervical cancers and impact of neoadjuvant chemotherapy.局部晚期宫颈癌患者前哨淋巴结状态及新辅助化疗的影响。
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Sentinel node procedures in gynecologic cancers: an overview.妇科恶性肿瘤前哨淋巴结活检术:概述。
Acta Obstet Gynecol Scand. 2012 Feb;91(2):174-81. doi: 10.1111/j.1600-0412.2011.01302.x. Epub 2011 Dec 20.
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Diagnostic value of intraoperative examination of sentinel lymph node in early cervical cancer: a prospective, multicenter study.早期宫颈癌中前哨淋巴结术中检查的诊断价值:一项前瞻性、多中心研究。
Gynecol Oncol. 2011 Nov;123(2):230-5. doi: 10.1016/j.ygyno.2011.08.010. Epub 2011 Sep 3.
6
Value of sentinel node mapping in cancer of the cervix.前哨淋巴结绘图在宫颈癌中的价值。
Gynecol Oncol. 2011 Aug;122(2):269-74. doi: 10.1016/j.ygyno.2011.04.002. Epub 2011 Apr 29.
7
Sentinel lymph node biopsy as guidance for radical trachelectomy in young patients with early stage cervical cancer.前哨淋巴结活检指导早期宫颈癌年轻患者行根治性子宫颈切除术。
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Global cancer statistics.全球癌症统计数据。
CA Cancer J Clin. 2011 Mar-Apr;61(2):69-90. doi: 10.3322/caac.20107. Epub 2011 Feb 4.
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Gynecol Oncol. 2011 Mar;120(3):347-52. doi: 10.1016/j.ygyno.2010.12.334. Epub 2011 Jan 8.
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