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Derivatives of (R,S)-1-N-(theophyllinyl-7'-ethyl)-amino-2-propanol with antiarrhythmic activity.

作者信息

Eckstein M, Zajaczkowska J, Samochowiec L, Maksjan M

机构信息

Department of Chemical Technology of Drugs, Copernicus Medical Academy, Kraków, Poland.

出版信息

Pol J Pharmacol Pharm. 1990 Jul-Aug;42(4):387-92.

PMID:2097599
Abstract

Three (R,S)-1-N-(theophyllinyl-7'-ethyl)-amino-2-propanol derivatives were obtained as soluble hydrochlorides and tested in four models of experimental arrhythmia. Two compounds 1a and 2 have shown antiarrhythmic properties and very low toxicity.

摘要

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