Derivatives of (R,S)-1-N-(theophyllinyl-7'-ethyl)-amino-2-propanol with antiarrhythmic activity.
作者信息
Eckstein M, Zajaczkowska J, Samochowiec L, Maksjan M
机构信息
Department of Chemical Technology of Drugs, Copernicus Medical Academy, Kraków, Poland.
出版信息
Pol J Pharmacol Pharm. 1990 Jul-Aug;42(4):387-92.
PMID:2097599
Abstract
Three (R,S)-1-N-(theophyllinyl-7'-ethyl)-amino-2-propanol derivatives were obtained as soluble hydrochlorides and tested in four models of experimental arrhythmia. Two compounds 1a and 2 have shown antiarrhythmic properties and very low toxicity.
摘要
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