Bui Marilyn M, Purohit Chetna N, Hakam Ardeshir
University of South Florida, Department of Pathology and Cell Biology, Tampa, Florida, USA.
Cytojournal. 2010 Sep 17;7:18. doi: 10.4103/1742-6413.70407.
Osteoclast-rich undifferentiated carcinoma of urinary bladder (ORUCUB) is a very rare and an unusual variant of high-grade urothelial carcinoma. Here, we report an extraordinary case of metastatic ORUCUB, diagnosed by fine needle aspiration (FNA) biopsy, in a 74-year-old Hispanic male who presented with a palpable, tender left groin mass and a known previous history of high-grade carcinoma of urinary bladder and prostatic cancer. To the best of our knowledge, diagnosis of ORUCUB by FNA is the first case report in FNA cytology to be published to date. A review of the literature is emphasized on the cytological, histological and immunohistochemical features and differential diagnoses of giant cell tumor.
富含破骨细胞的膀胱未分化癌（ORUCUB）是一种非常罕见且不寻常的高级别尿路上皮癌变体。在此，我们报告一例转移性ORUCUB的特殊病例，该病例通过细针穿刺（FNA）活检确诊，患者为一名74岁的西班牙裔男性，表现为左侧腹股沟可触及的压痛性肿块，既往有高级别膀胱癌和前列腺癌病史。据我们所知，通过FNA诊断ORUCUB是迄今为止发表的FNA细胞学领域的首例病例报告。本文着重回顾了文献中巨细胞瘤的细胞学、组织学和免疫组化特征以及鉴别诊断。
