The State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, the Chinese Academy of Sciences, Beijing 100101, China.
J Integr Plant Biol. 2010 Nov;52(11):996-1007. doi: 10.1111/j.1744-7909.2010.00967.x.
A major objective of quantitative trait locus (QTL) studies is to find genes/markers that can be used in breeding programs via marker assisted selection (MAS). We surveyed the QTLs for yield and yield-related traits and their genomic distributions in common wheat (Triticum aestivum L.) in the available published reports. We then carried out a meta-QTL (MQTL) analysis to identify the major and consistent QTLs for these traits. In total, 55 MQTLs were identified, of which 12 significant MQTLs were located on wheat chromosomes 1A, 1B, 2A, 2D, 3B, 4A, 4B, 4D and 5A. Our study showed that the genetic control of yield and its components in common wheat involved the important genes such as Rht and Vrn. Furthermore, several significant MQTLs were found in the chromosomal regions corresponding to several rice genomic locations containing important QTLs for yield related traits. Our results demonstrate that meta-QTL analysis is a powerful tool for confirming the major and stable QTLs and refining their chromosomal positions in common wheat, which may be useful for improving the MAS efficiency of yield related traits.
数量性状基因座（QTL）研究的主要目标是通过标记辅助选择（MAS）找到可用于育种计划的基因/标记。我们调查了在现有已发表的报告中普通小麦（Triticum aestivum L.）中产量和产量相关性状及其基因组分布的 QTL。然后，我们进行了元 QTL（MQTL）分析，以鉴定这些性状的主要和一致的 QTL。总共鉴定出 55 个 MQTL，其中 12 个重要的 MQTL 位于小麦染色体 1A、1B、2A、2D、3B、4A、4B、4D 和 5A 上。我们的研究表明，普通小麦产量及其组成的遗传控制涉及 Rht 和 Vrn 等重要基因。此外，在与产量相关性状的重要 QTL 对应的水稻基因组位置的染色体区域中发现了几个重要的 MQTL。我们的结果表明，元 QTL 分析是一种强大的工具，可用于确认普通小麦中主要和稳定的 QTL，并细化其染色体位置，这可能有助于提高与产量相关性状的 MAS 效率。
