用于 C-N 交叉偶联反应的多配体基 Pd 催化剂。
A multiligand based Pd catalyst for C-N cross-coupling reactions.
机构信息
Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.
出版信息
J Am Chem Soc. 2010 Nov 17;132(45):15914-7. doi: 10.1021/ja108074t. Epub 2010 Oct 27.
Abstract
An alternative approach to catalyst development, which led to a Pd catalyst based on two biarylphosphine ligands for C-N cross-coupling reactions, is reported. By effectively being able to take the form of multiple catalysts this system manifests the best properties that catalysts based on either of the two ligands exhibit separately and displays the highest reactivity and substrate scope of any system that has been reported to date for these reactions.
摘要
本文报道了一种用于 C-N 交叉偶联反应的钯催化剂的开发方法，该催化剂基于两种联芳基膦配体。通过能够有效地呈现出多种催化剂的形式，该体系表现出了两种配体分别作为催化剂所表现出的最佳性能，并显示出了迄今为止报道的此类反应中任何体系所具有的最高反应活性和底物范围。
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