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[4名兄弟中的肾上腺脑白质营养不良症]

[Adrenomyeloneuropathy in 4 brothers].

作者信息

Zhao X

机构信息

Dept Med Neurol, Ment Hosp. Prov Henan Xinxiang.

出版信息

Zhonghua Shen Jing Jing Shen Ke Za Zhi. 1990 Dec;23(6):360-2, 385.

PMID:2098249
Abstract

Four brothers with adrenomyeloneuropathy are reported. They have developed darkening of the skin the sign of adrenal insufficiency at age of 5-10. During 10 years after that time progressive spastic paraparesis has appeared gradually in all of them and has had aggrevative tendency abruptly in late. Three male cousins of the proband probably died of "juvenile type" of adrenoleucodystrophy.

摘要

报道了4例肾上腺脊髓神经病患者。他们在5至10岁时出现皮肤变黑,这是肾上腺功能不全的体征。此后10年间,他们均逐渐出现进行性痉挛性截瘫,且后期突然有加重趋势。先证者的3个男性堂兄弟可能死于“青少年型”肾上腺脑白质营养不良。

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