Kaup F J, Konstýr I, Drommer W
Veterinary Institute of Pathology, Hannover, FRG.
Exp Pathol. 1990;40(4):205-12. doi: 10.1016/s0232-1513(11)80298-7.
Epidemiological study of 340 Golden hamsters and 200 European hamsters bred as laboratory animals and necropsied between 1985 and 1989 in our facility (affiliation 2) revealed high incidence of spontaneous cysts. The incidence was in general higher in European (26 to 62%) than Golden hamsters (0 to 15%). The cysts, of different sizes, were localized first of all in the liver, and secondly (in European hamsters only), in the caecum wall. Light microscopic and electron microscopic examinations showed that the cysts are lined by flattened to cuboidal epithelial cells which, on their surface, have microvilli of different lengths and underneath a continuous basement membrane. These examinations lead further to the interpretation of the liver cysts as cystic distensions of the bile ducts. The cysts in the caecum wall could be interpreted as dilatations of the lymphatic vessels. As to the etiology, which remains unclear, several hypotheses are discussed.
1985年至1989年期间，在我们机构（单位2）对340只作为实验动物饲养并进行尸检的金黄仓鼠和200只欧洲仓鼠进行的流行病学研究显示，自发性囊肿的发生率很高。一般来说，欧洲仓鼠（26%至62%）的发生率高于金黄仓鼠（0%至15%）。不同大小的囊肿首先出现在肝脏，其次（仅在欧洲仓鼠中）出现在盲肠壁。光镜和电镜检查表明，囊肿内衬扁平至立方上皮细胞，其表面有不同长度的微绒毛，下方有连续的基底膜。这些检查进一步将肝囊肿解释为胆管的囊性扩张。盲肠壁中的囊肿可解释为淋巴管的扩张。关于病因，目前尚不清楚，文中讨论了几种假说。
