Somvanshi R, Iyer P K, Biswas J C, Koul G L
Livestock Production Research, Indian Veterinary Research Institute, Nainital.
J Comp Pathol. 1987 Sep;97(5):615-8. doi: 10.1016/0021-9975(87)90014-4.
Seven cases of multiple hepatic cysts of varying sizes and shapes were recorded in a closed colony of golden hamsters. Ante-mortem examination failed to show any clinical signs except for abdominal enlargement in one hamster. Multiple, thin-walled cysts of varying sizes (0.25 to 3.0 cm) and shape were observed in the liver. The larger cysts protruded from the liver surfaces and contained a colourless, clear, serous fluid and caused pathological change in 5-60 per cent of the hepatic parenchyma. Microscopically, the cysts were uni- or multilocular and lined by low cuboidal or flattened epithelial cells. The hepatic parenchyma around cysts showed pressure atrophy, necrosis, engorged sinusoids or other blood vessels or even haemorrhages, mild to extensive fatty or vacuolar degenerative changes and occasionally proliferation of biliary ducts.
在一个封闭的金黄仓鼠群体中记录到7例大小和形状各异的多发性肝囊肿。生前检查除一只仓鼠腹部膨隆外未发现任何临床症状。在肝脏中观察到多个大小不一（0.25至3.0厘米）、形状各异的薄壁囊肿。较大的囊肿从肝脏表面突出，内含无色、清亮的浆液性液体，导致5%至60%的肝实质发生病理改变。显微镜下，囊肿为单房或多房，内衬低立方上皮细胞或扁平上皮细胞。囊肿周围的肝实质显示受压萎缩、坏死、血窦或其他血管充血甚至出血、轻度至广泛的脂肪变性或空泡变性，偶尔还有胆管增生。
