Vasil'eva G I, Doroshenko E P, Kiseleva A K, Pustovalov V L
Zh Mikrobiol Epidemiol Immunobiol. 1990 Dec(12):83-6.
The possibility of using the reaction of macrophage disappearance (RMD) for the detection of delayed hypersensitivity (DH) to Y. pestis has been studied. As the result of these studies, RMD has been found suitable, in principle, for use in the quantitative evaluation of DH to Y. pestis. High sensitivity and specificity of this reaction have been established. The presence of DH in the process of the formation of immunity after immunization with Y. pestis antigen FIA has been shown. RMD can be observed during 28 days after immunization (the term of observation).
研究了利用巨噬细胞消失反应（RMD）检测对鼠疫耶尔森菌迟发型超敏反应（DH）的可能性。这些研究结果表明，RMD原则上适用于对鼠疫耶尔森菌DH的定量评估。已证实该反应具有高敏感性和特异性。已显示在用鼠疫耶尔森菌抗原FIA免疫后形成免疫的过程中存在DH。在免疫后28天（观察期）内可观察到RMD。
