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[庆尚北道浦项市沿香山河工业带华支睾吸虫病流行病学因素调查]

[A survey on the epidemiological factors of clonorchiasis in the Pohang industrial belt along the Hyungsan river, Kyongsangbuk-do].

作者信息

Kim S S, Han M H, Park S G, Lim H S, Hong S T

机构信息

Pohang Hospital, Medical College, Dong Guk University, Korea.

出版信息

Kisaengchunghak Chapchi. 1990 Dec;28(4):213-9. doi: 10.3347/kjp.1990.28.4.213.

Abstract

The employees at the Pohang industrial area, where Clonorchis sinensis has been known to be endemic along the Hyungsan River, were examined parasitologically for clonorchiasis and a part of the infected cases were surveyed with a questionnaire to outline the recent infection status of C. sinensis and epidemiological parameters in the area. Total of 3,180 cases were tested by intradermal inoculation of C. sinensis antigen (Green Cross Co., Korea), and 834 (26.2%) were found positive. Out of the positive cases, 598 were subjected to fecal examination for helminth ova. The examination revealed 129 (21.6%) ova positive cases of C. sinensis, and Trichuris trichiura 1.7%, Ascaris lumbricoides 0.3%, and Metagonimus yokogawai 0.2%. The questionnaire analysis showed some significant differences between the infected and non-infected (control) groups. The infected cases were less educated than the control, and they lived at the closer area to the river, and most of them lived there over 20 years. Also they preferred eating raw fresh water fish. Most of the detected cases were treated with praziquantel and found negative for the eggs in 85.3% of them 1 year after the treatment. The present data reveal markedly decreased endemicity of clonorchiasis compared with previous prevalence rates but still clonorchiasis is endemic in the Hyungsan river basin. A comprehensive measure including case detection, treatment and education for parasite control should be applied to control clonorchiasis in such endemic areas.

摘要

在浦项工业区,已知沿兴山江华支睾吸虫呈地方性流行,对该工业区的员工进行了华支睾吸虫病的寄生虫学检查,并对部分感染病例进行了问卷调查,以概述该地区华支睾吸虫的近期感染状况和流行病学参数。共有3180例接受了韩国绿十字公司生产的华支睾吸虫抗原皮内接种检测,其中834例(26.2%)呈阳性。在阳性病例中,598例接受了粪便蠕虫卵检查。检查发现129例(21.6%)华支睾吸虫卵阳性病例,鞭虫1.7%,蛔虫0.3%,横川后殖吸虫0.2%。问卷调查分析显示,感染组和未感染(对照)组之间存在一些显著差异。感染病例的受教育程度低于对照组,他们居住在离河流较近的地区,大多数人在那里居住了20多年。而且他们更喜欢吃生淡水鱼。大多数检测出的病例接受了吡喹酮治疗,治疗1年后85.3%的病例虫卵检测呈阴性。目前的数据显示,与以前的流行率相比,华支睾吸虫病的地方性明显降低,但在兴山江流域华支睾吸虫病仍然呈地方性流行。应采取包括病例检测、治疗和寄生虫控制教育在内的综合措施,以控制此类流行地区的华支睾吸虫病。

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