Park Do-Soon, Na Sung-Jin, Cho Shin Hyeong, June Kyung Ja, Cho Young-Chae, Lee Young-Ha
Graduate School of Public Health, Chungnam National University, Daejeon 301-131, Korea.
Department of Infection Biology, School of Medicine, Chungnam National University, Daejeon 301-131, Korea.
Korean J Parasitol. 2014 Aug;52(4):391-7. doi: 10.3347/kjp.2014.52.4.391. Epub 2014 Aug 29.
We evaluated the status of Clonorchis sinensis infection and potential risk factors among residents of riverside areas (Geumgang) in Muju-gun, Jeollabuk-do (Province), Korea. From January to February 2010, a total of 349 (171 males, 178 females) stool samples were collected and examined by the formalin-ether concentration technique. Also, village residents were interviewed using questionnaires to obtain information about C. sinensis infection-related risk factors. Overall egg-positive rate of C. sinensis was 13.2%. Egg-positive rates were significantly higher in males, farmers, and residents who had lived there more than 20 years, and in residents who had eaten raw freshwater fish than in opposite groups, respectively. However, there was no significant difference between age groups, education levels, cigarette smoking, alcohol drinking, health status, past history of infection, and experience of clonorchiasis medication and examination. Logistic regression analysis was performed to determine risk factors for clonorchiasis. On univariate analysis, the odds ratios for males, farmers, those who had lived there more than 20 years, and who had eaten raw freshwater fish were 2.41, 4.44, 3.16, and 4.88 times higher than those of the opposites, respectively. On multivariate analysis, the odds ratio of residents who had eaten raw freshwater fish was 3.2-fold higher than that of those who had not. These results indicate that residents living in Muju-gun, along the Geum River, Korea, have relatively high C. sinensis egg-positive rates, and the habit of eating raw freshwater fish was the major factor for the maintenance of clonorchiasis.
我们评估了韩国全罗北道茂朱郡锦江河畔地区（锦港）居民华支睾吸虫感染状况及潜在危险因素。2010年1月至2月，共采集了349份粪便样本（171名男性，178名女性），采用甲醛乙醚浓缩法进行检测。此外，还通过问卷调查对村民进行访谈，以获取与华支睾吸虫感染相关的危险因素信息。华支睾吸虫的总体虫卵阳性率为13.2%。男性、农民、居住超过20年的居民以及食用过生淡水鱼的居民的虫卵阳性率分别显著高于相应对照组。然而，年龄组、教育程度、吸烟、饮酒、健康状况、既往感染史以及华支睾吸虫病用药和检查经历之间没有显著差异。进行逻辑回归分析以确定华支睾吸虫病的危险因素。单因素分析显示，男性、农民、居住超过20年的居民以及食用过生淡水鱼的居民的优势比分别比相应对照组高2.41倍、4.44倍、3.16倍和4.88倍。多因素分析显示，食用过生淡水鱼的居民的优势比比未食用者高3.2倍。这些结果表明，韩国茂朱郡锦江河畔的居民华支睾吸虫虫卵阳性率相对较高，食用生淡水鱼的习惯是华支睾吸虫病持续存在的主要因素。
