Gilabert A, Salgado J, Franch A, Queralt J, Torralba A
Departament de Ciències Fisiològiques Humanes i de la Nutrició, Facultat de Farmacia, Universitat de Barcelona, Spain.
Rev Esp Fisiol. 1990 Dec;46(4):353-7.
Specific IgG and IgE antibodies against the mite Dermatophagoides pteronyssinus (Dp) have been determined in the serum of Sprague Dawley (SD) rats by enzyme linked immunosorbent assay (ELISA) and passive cutaneous anaphylaxis (PCA), respectively. Immunization of rats with Dp produces a rapid increase of serum specific IgE antibody levels which decrease when specific IgG antibodies start rising. The results indicate that the SD rat is a good model to induce a humoral immune response to allergen Dp.
分别通过酶联免疫吸附测定（ELISA）和被动皮肤过敏反应（PCA），测定了斯普拉格-道利（SD）大鼠血清中针对螨类屋尘螨（Dp）的特异性IgG和IgE抗体。用Dp免疫大鼠会使血清特异性IgE抗体水平迅速升高，而当特异性IgG抗体开始上升时，该水平会下降。结果表明，SD大鼠是诱导对过敏原Dp产生体液免疫反应的良好模型。
