Scalia S
Dipartimento di Scienze Farmaceutiche, Università di Ferrara, Italy.
J Pharm Biomed Anal. 1990;8(8-12):867-70. doi: 10.1016/0731-7085(90)80134-b.
A rapid high-performance liquid chromatographic method has been developed for the assay of 1,4-dioxane in ethoxylated fatty alcohol sulphates. After solid-phase extraction using Bakerbond C18 cartridges, samples were directly analysed on a LiChrospher CH-8 reversed-phase column with UV detection at 200 nm and an acetonitrile-water eluent. Recovery of 1,4-dioxane from the surfactant matrix was 95.7% in the 40 to 120 micrograms g-1 range. The minimum quantifiable amount was 18 micrograms g-1. The procedure is simple, reproducible, specific and suitable for routine analyses of commercial surfactants.
已开发出一种快速高效液相色谱法，用于测定乙氧基化脂肪醇硫酸盐中的1,4 - 二氧六环。使用Bakerbond C18柱进行固相萃取后，样品直接在LiChrospher CH - 8反相柱上进行分析，在200 nm处进行紫外检测，以乙腈 - 水为洗脱剂。在40至120微克/克的范围内，从表面活性剂基质中回收1,4 - 二氧六环的回收率为95.7%。最低可定量为18微克/克。该方法简单、可重复、特异，适用于商业表面活性剂的常规分析。
