Tinklenberg J, Brooks J O, Tanke E D, Khalid K, Poulsen S L, Kraemer H C, Gallagher D, Thornton J E, Yesavage J A
Veterans Administration Medical Center, Palo Alto, California.
Int Psychogeriatr. 1990 Fall;2(2):123-34. doi: 10.1017/s1041610290000382.
The Mini-Mental State Examination (MMSE) is a commonly used instrument for assessing mental impairment. Previous proposals for its underlying structure have focused on scores obtained from a single administration of the test. Because the MMSE is widely used in longitudinal studies, we examined the pattern of relations among the rates of chance of the items. Data were obtained from 63 subjects for 1.5 years or more. The relations among the rates of change of the MMSE items were described by a five-factor solution that accounted for 75% of the variance and comprised factors pertaining to orientation and concentration, obeying commands, learning and repetition, language, and recall. This was in contrast to the structure of the scores obtained from a single administration of the MMSE, which was best described by a two-factor solution. In order to provide a clinical validation, factor scores derived from the MMSE factors were used to predict scores on the Memory and Behavior Problems Checklist and the Brief Cognitive Rating Scale.
简易精神状态检查表（MMSE）是一种常用的评估精神损伤的工具。以往对其潜在结构的提议主要集中在单次测试所获得的分数上。由于MMSE在纵向研究中被广泛使用，我们研究了各项目变化率之间的关系模式。数据来自63名受试者，随访时间为1.5年或更长时间。MMSE项目变化率之间的关系由一个五因素模型描述，该模型解释了75%的方差，包括与定向和注意力、执行指令、学习和复述、语言及回忆相关的因素。这与单次MMSE测试所得分数的结构形成对比，后者用双因素模型描述最为合适。为了进行临床验证，从MMSE因素得出的因素分数被用于预测记忆与行为问题清单及简易认知评定量表的分数。
