McGill D B, Rakela J, Zinsmeister A R, Ott B J
Department of Medicine, Mayo Clinic, Rochester, Minnesota.
Gastroenterology. 1990 Nov;99(5):1396-400. doi: 10.1016/0016-5085(90)91167-5.
Nine thousand two hundred twelve liver biopsies were performed according to a defined protocol, and data were prospectively recorded to identify risk factors for major bleeding. There were 10 fatal and 22 nonfatal hemorrhages (0.11% and 0.24%, respectively). By comparison with a control group that did not hemorrhage, malignancy, age, sex, and the number of passes were the only predictable risk factors. The risk of fatal hemorrhage in patients with malignancy is estimated to be 0.4%; for nonfatal hemorrhage, 0.57%. In patients undergoing liver biopsy for nonmalignant disease, the risks are 0.04% and 0.16%, respectively.
按照既定方案进行了9212例肝脏活检，并前瞻性记录数据以确定大出血的危险因素。有10例致命性出血和22例非致命性出血（分别为0.11%和0.24%）。与未出血的对照组相比，恶性肿瘤、年龄、性别和穿刺次数是仅有的可预测危险因素。恶性肿瘤患者发生致命性出血的风险估计为0.4%；非致命性出血的风险为0.57%。在因非恶性疾病接受肝脏活检的患者中，相应风险分别为0.04%和0.16%。
