mRNA的密码子使用情况和二级结构
Codon usage and secondary structure of mRNA.
作者信息
Zama M
机构信息
Division of Biology, National Institute of Radiological Sciences, Chiba-shi, Japan.
出版信息
Nucleic Acids Symp Ser. 1990(22):93-4.
PMID:2101925
Abstract
The specific codon usage pattern of the repetitive unit nucleotide sequence of silk fibroin mRNA suggests that selection has operated on the codon usage to optimize the secondary structure characteristic of the mRNA. The correlation between the stability map of local secondary structure of type I collagen mRNA and the codon usage pattern and the translation rate of the collagen is also implied.
摘要
丝素蛋白信使核糖核酸重复单元核苷酸序列的特定密码子使用模式表明，选择作用于密码子使用，以优化信使核糖核酸的二级结构特征。这也暗示了I型胶原蛋白信使核糖核酸局部二级结构的稳定性图谱与密码子使用模式以及胶原蛋白翻译速率之间的相关性。
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