Berg H
Z Gesamte Inn Med. 1990 Dec 1;45(23):719-20.
In an open-controlled, randomized trial over 24 weeks, the serum uric acid lowering effect of a daily dose of 100 mg allopurinol in combination with 20 mg benzbromarone compared to 300 mg allopurinol only was investigated on a total of 60 patients suffering from hyperuricemia. Both preparations led to a decrease of the serum uric acid value to normal. In those patients however, who had received the combination the reduction of the serum uric acid level was more pronounced. Tolerance was generally good. Side-effects were not reported.
在一项为期24周的开放对照随机试验中，对60例高尿酸血症患者研究了每日剂量100毫克别嘌醇与20毫克苯溴马隆联合使用相比于仅使用300毫克别嘌醇的降血清尿酸效果。两种制剂均使血清尿酸值降至正常。然而，接受联合用药的患者血清尿酸水平降低更为明显。总体耐受性良好。未报告有副作用。
