Llajam M A
Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Br J Clin Pract. 1990 Dec;44(12):765.
In 1877, Dr Heinrich Koebner inflicted an experimental trauma on the uninvolved skin of a psoriatic patient. This resulted in the appearance of a typical psoriatic lesion at the site of trauma. This reaction, known as Koebner's phenomenon (KP), has subsequently been associated with several skin diseases. However, it has not been associated previously with necrobiosis lipoidica diabeticorum (NBL), a rare skin manifestation of diabetes mellitus. This report presents the unusual finding of NBL associated with KP in a patient with diabetes mellitus.
1877年，海因里希·科布纳医生对一名银屑病患者未受累的皮肤造成了实验性创伤。这导致创伤部位出现了典型的银屑病皮损。这种反应，即所谓的科布纳现象（KP），随后与多种皮肤病相关联。然而，此前它并未与糖尿病性类脂质渐进性坏死（NBL）相关联，NBL是糖尿病一种罕见的皮肤表现。本报告呈现了一名糖尿病患者中NBL与KP相关联这一不寻常的发现。
