Kowalczyk-Bronisz S H, Giełdanowski J, Bubak B
Department of Experimental Therapy, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław.
Arch Immunol Ther Exp (Warsz). 1990;38(3-4):229-38.
The effect of deltamethrin (10- or 30-day exposure) on selected parameters of humoral and cellular immune response in mice was studied. In parallel also hematologic and histologic examinations were performed. It was found that deltamethrin exerts negligible immunotropic effect. The prevailing was suppressive effect, and in some cases also stimulatory effect (PFC, GvH, Il-1, exogenous CFU-s). This negligible activity on the immunological system may be attributed to low toxicity of deltamehtrin in relation to the cells of immunological system or to too short exposure of the animals to its effect.
研究了溴氰菊酯(暴露10天或30天)对小鼠体液和细胞免疫反应选定参数的影响。同时还进行了血液学和组织学检查。发现溴氰菊酯产生的免疫otropic作用可忽略不计。主要是抑制作用,在某些情况下也有刺激作用(PFC、GvH、Il-1、外源性CFU-s)。这种对免疫系统可忽略不计的活性可能归因于溴氰菊酯对免疫系统细胞的低毒性或动物对其作用的暴露时间过短。