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依姆硫醇的药理学和免疫学特性研究。

Investigations on pharmacological and immunological properties of imuthiol.

作者信息

Giełdanowski J, Błaszczyk B, Raberger G, Duś D

机构信息

Department of Experimental Therapy, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław.

出版信息

Arch Immunol Ther Exp (Warsz). 1990;38(3-4):249-58.

PMID:1966367
Abstract

An observation was made that imuthiol exerts inhibitory effect on hemolysins forming cells (PFC) and on NK cells activity. It also reduces the number of T lymphocytes (in vitro), increases the activity of interleukin-1 and of the lymph node permeability factor. Well recognized is also its protective effect on thymocytes against hydrocortisone. Imuthiol was found to enhance rosette formation and to stimulate stem cells and partly suppressor cells. It reduces the level of cAMP. Its effect on the circulatory system is negligible.

摘要

有人观察到,免疫硫醇对溶血素形成细胞(PFC)和自然杀伤细胞活性具有抑制作用。它还能减少(体外)T淋巴细胞数量,增加白细胞介素-1和淋巴结通透因子的活性。其对胸腺细胞抗氢化可的松的保护作用也已得到充分认可。已发现免疫硫醇可增强玫瑰花结形成,刺激干细胞和部分抑制细胞。它会降低环磷酸腺苷(cAMP)水平。其对循环系统的影响可忽略不计。

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