Public Health Microbiology and Reference Laboratory, BC Centre for Disease Control, Vancouver, Canada.
Vector Borne Zoonotic Dis. 2011 Aug;11(8):1221-4. doi: 10.1089/vbz.2010.0062. Epub 2010 Oct 28.
Since its first detection in New York (1999), West Nile virus (WNv) has spread across the United States and Canada with the first activity reported in Canada in 2001. By 2004, WNv had been detected almost in every province of Canada and the contiguous regions of the United States with the exception of British Columbia (BC), this despite being detected in Alberta in 2003 and Washington as early as 2002. In August 2009, two human cases were serologically found to have WNv infection. They reported mosquito bites and had only traveled in the South and Central Okanagan areas of BC before their presentation. On the basis of clinical, laboratory, and epidemiological data, these two human cases have been confirmed as the first locally acquired WNv cases in BC. Various factors may have contributed to the 10-year delay in the spread of WNv to BC, including regional weather conditions and unique topography.
自 1999 年在纽约首次检测到西尼罗河病毒（WNv）以来，它已经传播到美国和加拿大，加拿大于 2001 年首次报告了该病毒的活动。到 2004 年，WNv 几乎已经在加拿大的每个省份和美国的毗邻地区被检测到，除了不列颠哥伦比亚省（BC），尽管 2003 年在艾伯塔省和 2002 年在华盛顿已经检测到了该病毒。2009 年 8 月，有两例人类病例经血清学检测发现感染了 WNv。他们报告说曾被蚊子叮咬，并且在出现症状之前只在不列颠哥伦比亚省的南奥卡纳根和中奥卡纳根地区旅行过。根据临床、实验室和流行病学数据，这两例人类病例被确认为不列颠哥伦比亚省首例本地获得的 WNv 病例。WNv 传播到不列颠哥伦比亚省的 10 年延迟可能与区域天气条件和独特的地形等多种因素有关。
