Department of Clinical Physiology and Nuclear Medicine, Imaging Center, Kuopio University Hospital, Kuopio, Finland.
J Clin Densitom. 2010 Oct-Dec;13(4):426-32. doi: 10.1016/j.jocd.2010.07.001.
Total hip arthroplasty (THA) is a traditional operative procedure in the treatment of osteoarthritis. The hip resurfacing arthroplasty (HRA) provides an alternative to the THA for young active patients. HRA is a bone-preserving procedure eliminating the problem of proximal femoral stress shielding and osteolysis associated to THA. Unfortunately, there is no standardized methodology to monitor the quality of bone after HRA. In this study, areal bone mineral density (BMD) in the operated hip (10 regions of interests [ROIs] of 34 volunteered HRA patients) was measured using Lunar Prodigy dual-energy X-ray absorptiometry, and the agreement of a standard (dual femur) and an orthopedic (orthopedic hip) acquisition modes was compared. Furthermore, reproducibility of the patient-specific analysis procedures was tested. The analysis procedures were reproducible with both acquisition modes (1.18%-1.37%). The mean (± standard deviation) difference between the acquisition modes was 1.46 ± 0.93%. At ROIs, a strong linear relationship was found between the results from 2 acquisition modes (R(2)=0.801-0.966, p<0.01). In conclusion, both acquisition modes were reproducible, and it is suggested that the error induced by the different acquisition modes does not affect interpretation of BMD changes after HRA surgery.
全髋关节置换术（THA）是治疗骨关节炎的传统手术方法。髋关节表面置换术（HRA）为年轻活跃的患者提供了THA 的替代方案。HRA 是一种保留骨的手术，可消除与 THA 相关的股骨近端应力遮挡和骨溶解问题。不幸的是，目前尚无标准化方法来监测 HRA 后骨的质量。在这项研究中，使用 Lunar Prodigy 双能 X 射线吸收仪测量了接受手术的髋关节的面积骨密度（BMD）（34 名自愿接受 HRA 治疗的患者的 10 个感兴趣区域[ROI]），并比较了标准（双股骨）和矫形（矫形髋关节）采集模式的一致性。此外，还测试了患者特定分析程序的可重复性。两种采集模式（1.18%-1.37%）都具有可重复性。两种采集模式之间的平均（±标准差）差异为 1.46±0.93%。在 ROI 中，两种采集模式之间存在很强的线性关系（R²=0.801-0.966，p<0.01）。总之，两种采集模式均具有可重复性，并且建议不同采集模式引起的误差不会影响对 HRA 手术后 BMD 变化的解释。
