肱动脉搏动指数变化的可重复性优于血流介导的血管舒张。
Pulsatility index change of brachial artery shows better reproducibility than flow-mediated vasodilation.
机构信息
Departamento de Ginecologia e Obstetrícia da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo, Ribeirão Preto, São Paulo, Brazil.
出版信息
Ultrasound Med Biol. 2010 Dec;36(12):2036-41. doi: 10.1016/j.ultrasmedbio.2010.09.005. Epub 2010 Oct 28.
We aim to evaluate intra- and interobserver reproducibility of brachial artery flow-mediated dilation (FMD) and of pulsatility index change (PI-C) 1 min after a 5-min forearm compression in pregnant women. Flow-mediated dilation and PI-C were assessed in 31 healthy pregnant women in 3 consecutive days, by two observers. A broader range of response to the stimulus was observed for PI-C (-58.99%-86.71%) than FMD (2.38%-27.01%). The intraclass correlation coefficients were higher for PI-C than for FMD (intra = 0.90 vs. 0.69, p = 0.047; inter = 0.94 vs. 0.61, p = 0.007). Therefore, PI-C measurements were more reliable than FMD. However, studies comprising of subjects with cardiovascular risk factors relating FMD and PI-C become necessary to validate this method for the study of endothelial dysfunction.
我们旨在评估在 5 分钟前臂压迫后 1 分钟肱动脉血流介导的扩张（FMD）和搏动指数变化（PI-C）的观察者内和观察者间的可重复性。通过两位观察者在 3 天内对 31 名健康孕妇进行了 FMD 和 PI-C 评估。PI-C（-58.99％-86.71％）的反应范围比 FMD（2.38％-27.01％）更广泛。PI-C 的组内相关系数高于 FMD（内 = 0.90 对 0.69，p = 0.047；间 = 0.94 对 0.61，p = 0.007）。因此，PI-C 测量比 FMD 更可靠。然而，有必要对具有与 FMD 和 PI-C 相关的心血管危险因素的受试者进行研究，以验证该方法用于研究内皮功能障碍。
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