Aswini Y B, Varun S
Department of Preventive and Community Dentistry, Teerthankar Mahaveer Dental college and Research Center, Delhi Road, Moradbad, Uttar Pradesh, India.
Indian J Hum Genet. 2010 May;16(2):47-54. doi: 10.4103/0971-6866.69326.
The availability and the integration of genetic information into our understanding of normal and abnormal growth and development are driving important changes in health care. These changes have fostered the hope that the availability of genetic information will promote a better understanding of disease etiology and permit early, even pre-symptomatic diagnosis and preventive intervention to avoid disease onset. Hence, our aim was to review and provide the insight into the role of genetics in public health and its scope as well as barriers. The use of genetics along with their goals and essential public health functions are discussed. From the era of eugenics to the present era, this area has seen many turns in which geneticists have put through their effort to tie together the strings of both molecular genetics and public health. Though still the dark clouds of eugenics, the predictive power of genes, genetic reductionism, non-modifiable risk factors, individuals or populations, resource allocation, commercial imperative, discrimination and understanding and education are hanging above. The technological and scientific advances that have fundamentally changed our perception of human diseases fuel the expectations for this proactive health.
遗传信息的可得性以及将其整合到我们对正常和异常生长发育的理解中，正在推动医疗保健领域的重大变革。这些变革催生了一种希望，即遗传信息的可得性将促进对疾病病因的更好理解，并允许进行早期甚至症状前诊断以及预防性干预，以避免疾病发作。因此，我们的目的是回顾并深入探讨遗传学在公共卫生中的作用及其范围和障碍。讨论了遗传学的应用及其目标和基本公共卫生功能。从优生学时代到现在，这个领域经历了许多转变，遗传学家们努力将分子遗传学和公共卫生的线索联系在一起。尽管优生学的阴霾、基因的预测能力、基因还原论、不可改变的风险因素、个体或群体、资源分配、商业需求、歧视以及理解和教育等问题仍然存在。从根本上改变了我们对人类疾病认知的技术和科学进步，激发了人们对这种积极主动式健康的期望。
