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[三叉神经感觉根表面束切断术:一种治疗三叉神经痛的新束切断术]

[Surface tractotomy of trigeminal nerve sensory root:a new tractotomy for the treatment of trigeminal neuralgia].

作者信息

Jiang Yuashi, Yang Weiyan, Zhong Shizhen, Huang Zongqing, Zhuang Junhun, Zhang Changchun, Chen Jinsheng, Wei Peiyong

机构信息

Department of Otolaryngology Head and Neck Surgery, the Fourth Hospital, Shenzhen, 518033, China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2010 Aug;24(16):721-4.

Abstract

OBJECTIVE

To evaluate the feasibility of surface tractotomy of trigeminal nerve sensory root (STS) for the treatment of trigeminal neuralgia (TN).

METHOD

Seven patients with TN were operated on using the STS. The six patients were followed up for 4.8-9.8 years. The trigeminal nerve root (TNR) obtained from 30 cadavers were performed microanatomical research using paraffin embedding and hematoxylin-eosin staining technique.

RESULT

Clinically, the patients' symptoms, such as face ache, disappeared after the surface nerve fiber bundles of trigeminal nerve sensory root (TNSR) were cut off. Only one patient died of brainstem bleeding on postoperative day 18. Histological examination: The common type of sensory root fibers were arranged parallel for 3-6 mm at its exit of brainstem, and then the glial myelin transformed to Schwann cells. The axon bifurcated from outer layer to middle region, and gradually formed the tiny nerve fiber bundles in the surface layer and the giant nerve fiber bundles in the center of the root.

CONCLUSION

TN can be radical cured by STS without lesioning of nerve functions. Therefore,this new approach is an effective, advanced surgical technique for TN treatment.

摘要

目的

评估三叉神经感觉根表面束切断术(STS)治疗三叉神经痛(TN)的可行性。

方法

7例TN患者接受了STS手术。6例患者进行了4.8 - 9.8年的随访。对取自30具尸体的三叉神经根(TNR)采用石蜡包埋和苏木精 - 伊红染色技术进行显微解剖学研究。

结果

临床上,切断三叉神经感觉根(TNSR)的表面神经纤维束后,患者面部疼痛等症状消失。仅1例患者于术后第18天死于脑干出血。组织学检查:感觉根纤维的常见类型在其脑干出口处平行排列3 - 6毫米,然后神经胶质髓鞘转变为施万细胞。轴突从外层分叉至中间区域,并逐渐在表层形成微小神经纤维束,在根中心形成巨大神经纤维束。

结论

STS可根治TN且不损伤神经功能。因此,这种新方法是一种治疗TN的有效、先进的外科技术。

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