Savel'ev V N, Babenyshev B V, Savel'eva I V, Vasil'eva O V, Guseva L V, Grizhebovskiĭ G M, Kurbanov Sh Kh, Asvarov B M, Batyrova B A, Doroshenko I G, Antonenko A D
Antibiot Khimioter. 2010;55(5-6):8-13.
The data on antibacterial susceptibility and resistance of Vibrio cholerae eltor phenotypes with different sets of the susceptibility or resistance markers conditioning the outbreaks and sporadic cases of cholera in the Caucasus within 1970-1998 are presented. An increase of the number of the Vibrio cholerae phenotypes resistant to tetracycline and chloramphenicol usually used in the treatment of cholera was recorded in 1990-1994 vs. 1970-1989. The El Tor cholera vibrios stored on synthetic media lost some of their resistance markers, therefore the retrospective investigation of the antibioticograms was only of approximate prognostic value in the choice of the drugs for the etiotropic treatment of cholera in view of possible outbreak of the disease.
本文呈现了1970 - 1998年间高加索地区霍乱暴发和散发病例中，不同组别的易感性或抗性标记条件下霍乱弧菌埃尔托生物型的抗菌药敏性和抗性数据。与1970 - 1989年相比，1990 - 1994年记录到对通常用于治疗霍乱的四环素和氯霉素耐药的霍乱弧菌生物型数量有所增加。保存在合成培养基上的埃尔托霍乱弧菌失去了一些抗性标记，因此鉴于可能爆发的疾病，对抗生素药敏谱的回顾性调查在选择霍乱病因治疗药物方面仅具有近似的预后价值。
