Salim Máttar V
Departamento de Microbiología, Universidad Javeriana, Facultad de Ciencias, Bogotá, Colombia.
Enferm Infecc Microbiol Clin. 1992 Nov;10(9):525-30.
Cholera is an infectious transmissible disease characterized by the development of secretory diarrhea and that presents in epidemic and endemic forms. In Latin-America we are currently seen what could be the eight pandemic in cholera history, due to Vibrio cholerae 0:1 El Tor, Inaba serotype, infection. In the present preliminary study we analyze 300 patients with a clinical picture suggesting cholerae. In 250 cases, Vibrio cholerae 0:1 strains were isolated. The identification was made using mainly the following test and procedures: 1) growth in TCBS (saccharose fermentation), 2) Reactivity with sodium desoxycholate, 3) Oxidase-cytochrome test and 4) agglutination with polyvalent antisera. All isolated Vibrio cholerae strains 0:1 were sensitive to tetracycline, trimethoprim-sulfamethoxazole, norfloxacin, ciprofloxacin and gentamicin, but were resistant to ampicillin. This report summarizes the main features of Vibrio cholerae 0:1 El Tor, Inaba serotype, isolated in Colombian cholera epidemic.
霍乱是一种传染性可传播疾病，其特征为分泌性腹泻，并以流行和地方流行形式出现。在拉丁美洲，由于霍乱弧菌0:1埃尔托生物型、稻叶血清型感染，我们目前正目睹霍乱历史上可能的第八次大流行。在本初步研究中，我们分析了300例临床症状提示霍乱的患者。在250例病例中，分离出了霍乱弧菌0:1菌株。鉴定主要采用以下试验和程序：1）在TCBS（蔗糖发酵）培养基上生长；2）与去氧胆酸钠的反应性；3）氧化酶-细胞色素试验；4）用多价抗血清进行凝集试验。所有分离出的霍乱弧菌0:1菌株对四环素、甲氧苄啶-磺胺甲恶唑、诺氟沙星、环丙沙星和庆大霉素敏感，但对氨苄西林耐药。本报告总结了在哥伦比亚霍乱流行中分离出的霍乱弧菌0:1埃尔托生物型、稻叶血清型的主要特征。
