中国巨鹿县活产新生儿围产结局的 12 个月前瞻性调查。

A 12-month prospective survey of perinatal outcome of liveborn neonates in Julu County, China.

机构信息

Department of Pediatrics, Children's Hospital of Fudan University, Shanghai, China.

出版信息

Chin Med J (Engl). 2010 Oct;123(20):2781-5.

Abstract

BACKGROUND

Population based epidemiologic study on the main diseases and birth status of liveborn neonates remains scarce in China, especially in rural areas where a large number of neonates are born. The aim of this study was to establish an epidemiological basis of live births in Julu County, a representative of the northern and mid-western parts of China in terms of demography, disease pattern and women and children's health care infrastructure.

METHODS

The perinatal data of all live births were prospectively collected in three participating county-level hospitals from September 1, 2007 to August 30, 2008.

RESULTS

There were 5822 live births in these hospitals. Among all live births, 53.7% were male and 4.5% were born prematurely. Mean (SD) birth weight (BW) was (3348 ± 503) g. The low (< 2500 g) and very low BW (< 1500 g) infants accounted for 3.8% and 0.5% of the total births, with 6.5% as small for gestational age and 2.8% as multi-births. Cesarean section rate was 30.2%, of which 68.6% were elective. There were 745 infants (12.8% of the live births) admitted to local neonatal wards within 7 days of postnatal life, in which 48.3% and 19.3% were due to perinatal asphyxia and prematurity, respectively. The incidences of perinatal aspiration syndrome, transient tachypnea and respiratory distress syndrome were 4.9%, 0.6% and 0.5%, respectively. Neonatal mortality was 7.6‰ (44/5822), with 16 in delivery room and 28 in neonatal ward before discharge.

CONCLUSIONS

This study provided a population-based perinatal data of live births and neonatal mortality in a northern China county with limited resources. Neonatal disorders related to perinatal asphyxia remain a serious clinical problem, which calls for sustained education of advanced neonatal resuscitation and improvement in the quality of perinatal-neonatal care.

摘要

背景

在中国，人口基础上的主要疾病和活产儿出生状况的流行病学研究仍然很少，特别是在大量新生儿出生的农村地区。本研究的目的是为中国北方和中西部地区的一个代表性地区——巨鹿县的活产儿建立一个流行病学基础，这些地区在人口统计学、疾病模式以及妇女和儿童保健基础设施方面具有代表性。

方法

2007 年 9 月 1 日至 2008 年 8 月 30 日，在三家参与的县级医院前瞻性地收集所有活产儿的围产儿数据。

结果

这些医院共有 5822 例活产儿。所有活产儿中，男性占 53.7%，早产儿占 4.5%。平均（SD）出生体重（BW）为（3348±503）g。低体重（<2500g）和极低体重（<1500g）婴儿分别占总出生人数的 3.8%和 0.5%，6.5%为小于胎龄儿，2.8%为多胎。剖宫产率为 30.2%，其中 68.6%为选择性剖宫产。在产后 7 天内，有 745 例（活产儿的 12.8%）婴儿入住当地新生儿病房，其中 48.3%和 19.3%分别因围产期窒息和早产而入住。围产期吸入综合征、短暂性呼吸急促和呼吸窘迫综合征的发生率分别为 4.9%、0.6%和 0.5%。新生儿死亡率为 7.6‰（44/5822），其中 16 例在产房，28 例在新生儿病房出院前。